At a glance
A tripeptide investigated in neuronal stress and gene-regulation models.
This profile separates the compound’s scientific background from specification-specific preparation and source schedules. Begin with the research findings and limitations, then select the formulation you want to examine.
How it works
Potential benefits & side effects
Interpret each outcome in the context of the study population, formulation and evidence type. Research findings do not establish a personal treatment outcome.
Potential benefits & research findings
The cited work explores experimental neuroprotection and related outcomes. Short research courses described in days should retain that duration rather than being expanded into an eight-week schedule.[3][9][6]
Read the original publications to see the measured endpoints, comparator, duration and uncertainty. Mechanistic plausibility and a favorable experimental result are different from demonstrated clinical benefit.
Side effects & evidence limitations
Interpret the reported adverse effects together with the study population, route and observation period. Small or short studies can miss uncommon and delayed harms. Evidence from a related compound does not establish the safety of Pinealon.
Source-reported adverse effects and cautions
Sources are available for independent reading. Individual claims and research schedules have not yet undergone an independent clinical review by Pep Science.
- Editorial responsibility
- Pep Science editorial desk
- Last independent review
- Not yet recorded
SPECIFICATIONS & SOURCE SCHEDULES
Explore a vial size
Select the exact formulation. Vial content, target dose and prepared concentration are different measurements.
Showing 20 mg · 1 source tables
Standard Approach (3 mL = ~6.67 mg/mL)
| Days | Daily Dose | Units (per injection) (mL) |
|---|---|---|
| Days 1–5 | 1.0 mg (1,000 mcg) | 15 units (0.15 mL) |
| Days 6–14 | 1.5 mg (1,500 mcg) | 22.5 units (0.225 mL) |
| Days 15–20 | 2.0 mg (2,000 mcg) | 30 units (0.30 mL) |
Frequency: Inject once daily subcutaneously, preferably in the morning or early afternoon. Standard cycles are 10–20 days, with the option to extend to 28 days if desired[5][6]. Repeat cycles can be administered every 2–3 months as needed.
Additional schedule context & duration
Concise summary of the once‑daily regimen.
- Goal: Support neuroprotection, cognitive function, and cellular resilience in brain tissue through peptide bioregulation[3][7].
- Schedule: Daily subcutaneous injections for 10–20 days (extendable to 28 days).
- Dose Range: 1.0–2.0 mg daily with gradual titration.
- Reconstitution: 3.0 mL per 20 mg vial (~6.67 mg/mL) for accurate unit measurements.
- Storage: Lyophilized frozen; reconstituted refrigerated; avoid repeated freeze–thaw.
Suggested daily titration approach.
- Start: 1.0 mg daily for Days 1–5 to assess tolerance.
- Increase: 1.5 mg daily for Days 6–14.
- Target: 2.0 mg daily for Days 15–20 (or up to Day 28 if extending cycle).
- Frequency: Once per day (subcutaneous), preferably morning or early afternoon.
- Cycle Length: Standard 10–20 days; repeat cycles every 2–3 months.
- Timing: Consistent daily timing; rotate injection sites.
Preparation
Reconstitution Steps
- Draw 3.0 mL bacteriostatic water with a sterile syringe.
- Inject slowly down the vial wall; avoid foaming.
- Gently swirl/roll until dissolved (do not shake).
- Label and refrigerate at 2–8 °C (35.6–46.4 °F), protected from light.
Storage Instructions
Proper storage preserves peptide quality.
- Lyophilized: Store at −20 °C (−4 °F) in dry, dark conditions; minimize moisture exposure.
- Reconstituted: Refrigerate at 2–8 °C (35.6–46.4 °F); prepare aliquots if needed and avoid freeze–thaw.
- Allow vials to reach room temperature before opening to reduce condensation uptake.
Injection Technique
General subcutaneous guidance from clinical best‑practice resources[16].
- Clean the vial stopper and skin with alcohol; allow to dry.
- Pinch a skinfold; insert the needle at 45–90° into subcutaneous tissue[17][18].
- Do not aspirate for subcutaneous injections; inject slowly and steadily[17].
- Rotate sites systematically (abdomen, thighs, upper arms) to avoid lipohypertrophy[19].
Materials & quantity planning
Source materials checklist · 20 mg
Plan based on standard 10–20 day cycles with once‑daily administration.
-
Peptide Vials (Pinealon, 20 mg each):
- 10‑day cycle ≈ 1 vial
- 20‑day cycle ≈ 2 vials
- 28‑day cycle ≈ 3 vials
-
Insulin Syringes (U‑100):
- Per day: 1 syringe
- 10‑day cycle: 10 syringes
- 20‑day cycle: 20 syringes
- 28‑day cycle: 28 syringes
-
Bacteriostatic Water (10 mL bottles): Use 3.0 mL per vial for reconstitution.
- 10‑day cycle (1 vial): 3 mL → 1 × 10 mL bottle
- 20‑day cycle (2 vials): 6 mL → 1 × 10 mL bottle
- 28‑day cycle (3 vials): 9 mL → 1 × 10 mL bottle
-
Alcohol Swabs: One for the vial stopper + one for the injection site each day.
- Per day: 2 swabs
- 10‑day cycle: 20 swabs
- 20‑day cycle: 40 swabs
- 28‑day cycle: 56 swabs → recommend 1 × 100‑count box
Calculate a phased quantity
Enter each finite phase from the schedule you are studying. Open-ended phases need an explicit duration. Calculation uses 20 mg per vial and 3 mL per vial.
Complete each phase to calculate totals.
Quantity estimates exclude preparation losses and expiry. Follow the formulation’s handling and disposal requirements.
FOLLOW THE EVIDENCE
References & further reading
Original publications and source documents cited across this product’s variants. A listed source is not an independent endorsement of a dosing schedule.
- 01
Research publication
Biogerontology (Springer) — Peptide bioregulation of aging: 35‑year research overview by Khavinson and Anisimov (opens in a new tab)pubmed.ncbi.nlm.nih.gov
Back to overview ↑ - 03
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- 07
Source document
Paragon Sports Medicine — Pinealon peptide: brain health, memory, and cognitive enhancement research (opens in a new tab)www.paragonsportsmedicine.com
Back to overview ↑ - 08
Source document
Core Peptides Research — Pinealon effects on neuroprotection, cell vitality, and aging processes (opens in a new tab)www.corepeptides.com
Back to overview ↑ - 09
Research publication
PMC (PubMed Central) — Pinealon protects rat offspring from prenatal hyperhomocysteinemia and cognitive deficits (opens in a new tab)pmc.ncbi.nlm.nih.gov
Back to overview ↑ - 10
Research publication
Doklady Biological Sciences — Regulatory peptides protect brain neurons from hypoxia in vivo (opens in a new tab)pubmed.ncbi.nlm.nih.gov
Back to overview ↑ - 11
Research publication
PubMed — Effects of synthetic peptides in patients with chronic polymorbidity and organic brain syndrome (opens in a new tab)pubmed.ncbi.nlm.nih.gov
Back to overview ↑ - 13
Source document
Peptide Sciences Research — Pinealon research: reduction of caspase‑3 and free radical damage (opens in a new tab)www.peptidesciences.com
Back to overview ↑ - 15
Research publication
Advances in Gerontology — Clinical efficacy of peptide bioregulators: comprehensive review and safety profile (opens in a new tab)pubmed.ncbi.nlm.nih.gov
Back to overview ↑ - 16
Research publication
PMC (Subcutaneous Drug Injection Review) — Pharmacologic considerations of the subcutaneous route (opens in a new tab)pmc.ncbi.nlm.nih.gov
Back to overview ↑ - 17
Public health resource
CDC — Vaccine administration: subcutaneous route (angle/site; no aspiration) (opens in a new tab)www.cdc.gov
Back to overview ↑ - 18
Public health resource
CDC (Subcut Injection PDF) — Technique diagram and site guidance for subcutaneous injections (opens in a new tab)www.cdc.gov
Back to overview ↑ - 19
Public health resource
NCBI Bookshelf — Best practices for injection (asepsis, preparation, and administration) (opens in a new tab)www.ncbi.nlm.nih.gov
Back to overview ↑
Continue exploring
Related topics are not interchangeable compounds or formulations.