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Metabolic research · RESEARCH PROFILE

AOD-9604

A growth-hormone-derived fragment investigated for effects on fat metabolism.

2 specifications·13 source documents·Source updated Jun 14, 2026

At a glance

A growth-hormone-derived fragment investigated for effects on fat metabolism.

This profile separates the compound’s scientific background from specification-specific preparation and source schedules. Begin with the research findings and limitations, then select the formulation you want to examine.

How it works

AOD-9604 was designed around a portion of the growth hormone sequence. Research asks whether selected effects on lipid handling can be separated from the wider actions of full-length growth hormone.[1][4][9]

Potential benefits & side effects

Interpret each outcome in the context of the study population, formulation and evidence type. Research findings do not establish a personal treatment outcome.

Potential benefits & research findings

The literature includes laboratory work and weight-related clinical investigations. Study design, formulation and the size of the observed effect matter more than a general “fat-loss peptide” label.[10][2][3]

Read the original publications to see the measured endpoints, comparator, duration and uncertainty. Mechanistic plausibility and a favorable experimental result are different from demonstrated clinical benefit.

Side effects & evidence limitations

Interpret the reported adverse effects together with the study population, route and observation period. Small or short studies can miss uncommon and delayed harms. Evidence from a related compound does not establish the safety of AOD-9604.

Source-reported adverse effects and cautions

  • Does not meaningfully raise IGF‑1 and shows a placebo‑like safety profile in human studies; no anti‑AOD9604 antibodies detected[2][3].
  • Generally well tolerated; occasional mild injection‑site reactions (redness/itch) may occur with subcutaneous administration.
  • Sources are available for independent reading. Individual claims and research schedules have not yet undergone an independent clinical review by Pep Science.

    Editorial responsibility
    Pep Science editorial desk
    Last independent review
    Not yet recorded
    Editorial standards & corrections

    SPECIFICATIONS & SOURCE SCHEDULES

    Explore a vial size

    Select the exact formulation. Vial content, target dose and prepared concentration are different measurements.

    Showing 2 mg · 1 source tables

    Source-derived research information. Table phases retain the source’s actual duration; open-ended phases are not converted into a fixed eight-week course. Review the original study before interpreting a schedule.

    Standard / Gradual Approach (3 mL = ~0.667 mg/mL)

    Weeks 1–4Weeks 5–12
    WeekDaily Dose (mcg)Units (per injection) (mL)
    Weeks 1–4300 mcg45 units (0.45 mL)
    Weeks 5–12500 mcg75 units (0.75 mL)

    Frequency: Inject once daily subcutaneously (typically in the morning on an empty stomach). This schedule uses the largest practical dilution (3.0 mL) to keep per‑injection units ≥10 for better accuracy. Rotate injection sites (abdomen, thighs, upper arms) to minimize local irritation.

    Additional schedule context & duration

    Concise summary of the once‑daily regimen.

    • Goal: Support reduction of fat mass and enhance fat oxidation over time[1][4].
    • Schedule: Daily subcutaneous injections for 8–12 weeks (extend to 16 weeks if desired).
    • Dose Range: 300–500 mcg daily with gradual titration.
    • Reconstitution: 3.0 mL per 2 mg vial (~0.667 mg/mL) for accurate unit measurements.
    • Storage: Lyophilized frozen; reconstituted refrigerated; avoid repeated freeze–thaw.

    Suggested daily titration approach.

    • Start: 300 mcg daily for Weeks 1–4; increase to 500 mcg for Weeks 5–12 as tolerated.
    • Target: 500 mcg daily by Week 5 and maintain through cycle completion.
    • Frequency: Once per day (subcutaneous).
    • Cycle Length: 8–12 weeks; optional extension to 16 weeks.
    • Timing: Morning administration (fasted) is common; rotate injection sites.

    Read this protocol on Pep Science → · View cited documents ↓

    Preparation

    Preparation and stability depend on the formulation, diluent, container and handling. The source-specific notes below apply to the selected record.
    Reconstitution Steps
    1. Draw 3.0 mL bacteriostatic water with a sterile syringe.
    2. Inject slowly down the vial wall; avoid foaming.
    3. Gently swirl/roll until dissolved (do not shake).
    4. Label and refrigerate at 2–8 °C (35.6–46.4 °F), protected from light.

    Important: This guide is for educational purposes only and is not medical advice. For research use only. Not for human consumption.

    Storage Instructions

    Proper storage preserves peptide quality.

    • Lyophilized: Store at −20 °C (−4 °F) in dry, dark conditions; stable for 1+ year[5].
    • Reconstituted: Refrigerate at 2–8 °C (35.6–46.4 °F); use within 3–4 weeks and avoid freeze–thaw[6].
    • Allow vials to reach room temperature before opening to reduce condensation uptake.

    Injection Technique

    General subcutaneous guidance from clinical best‑practice resources[7].

    • Clean the vial stopper and skin with alcohol; allow to dry completely[8].
    • Pinch a skinfold; insert the needle at 90° (or 45° if very little subcutaneous fat) into subcutaneous tissue[7].
    • Do not aspirate for subcutaneous injections; inject slowly and steadily[13].
    • Rotate sites systematically (abdomen at least 2 inches from navel, thighs, upper arms) to avoid lipohypertrophy[8].

    Materials & quantity planning

    Source materials checklist · 2 mg

    Plan based on an 8–12 week daily protocol with gradual titration (300 mcg Weeks 1–4, 500 mcg Weeks 5+).

    • Peptide Vials (AOD-9604, 2 mg each):

      • 8 weeks ≈ 12 vials
      • 12 weeks ≈ 19 vials
      • 16 weeks ≈ 26 vials
    • Insulin Syringes (U‑100):

      • Per week: 7 syringes (1/day)
      • 8 weeks: 56 syringes
      • 12 weeks: 84 syringes
      • 16 weeks: 112 syringes
    • Bacteriostatic Water (10 mL bottles): Use 3.0 mL per vial for reconstitution.

      • 8 weeks (12 vials): 36 mL4 × 10 mL bottles
      • 12 weeks (19 vials): 57 mL6 × 10 mL bottles
      • 16 weeks (26 vials): 78 mL8 × 10 mL bottles
    • Alcohol Swabs: One for the vial stopper + one for the injection site each day.

      • Per week: 14 swabs (2/day)
      • 8 weeks: 112 swabs → recommend 2 × 100‑count boxes
      • 12 weeks: 168 swabs → recommend 2 × 100‑count boxes
      • 16 weeks: 224 swabs → recommend 3 × 100‑count boxes

    Calculate a phased quantity

    Enter each finite phase from the schedule you are studying. Open-ended phases need an explicit duration. Calculation uses 2 mg per vial and 3 mL per vial.

    Complete each phase to calculate totals.

    Quantity estimates exclude preparation losses and expiry. Follow the formulation’s handling and disposal requirements.

    FOLLOW THE EVIDENCE

    References & further reading

    Original publications and source documents cited across this product’s variants. A listed source is not an independent endorsement of a dosing schedule.

    COMMUNITY · EXTERNAL FORUM

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